博士，特聘教授，博士生导师。入选湖北省有关人才计划（2021年），武汉工程大学第四层次人才（2021年）。2015年6月博士毕业于中南大学资源加工与生物工程学院，获微生物学博士学位（导师：邱冠周院士、刘学端教授、许玫英研究员）。先后在广东省科学院广东省微生物研究所、中国地质大学（武汉）、美国迈阿密大学进行博士后研究。主要从事污染物微生物降解转化与资源开发、极端环境微生物领域的研究，现已主持国家自然科学基金面上项目、国家自然科学基金青年科学基金项目、中国博士后科学基金面上项目，并作为骨干参与国家自然科学基金重大研究计划重点项目、国家科技部重点研发计划项目、广东省省级科技计划项目等，取得了多项具有国际水平、创新性的研究成果。在The ISME Journal、Journal of Hazardous Materials、Environmental Science& Technology等国际期刊发表论文30余篇，申请授权国家专利5项。 现担任Soil Ecology Letters、Frontiers in Microbiology、Frontiers of Environmental Science & Engineering等国际期刊的审稿专家。
联系方式
fangy@wit.edu.cn; fangyun1987@126.com;
专业领域
环境微生物；工业微生物；生物技术与工程；生物化工；发酵工程；生物冶金
研究方向
1、 矿山、热泉、盐湖等极端环境中抗逆性微生物资源多样性；
2、 逆境胁迫下微生物调控的生理机制；
3、 微生物生态调控技术开发与应用；
4、 微生物驱动的元素循环；
5、 稀土生物冶金；
教育工作经历
2005/09-2009/06 中南大学资源加工与生物工程学院，生物工程，学士；
2009/09-2015/06 中南大学资源加工与生物工程学院，微生物学，博士；
2011/09-2015/06 广东省微生物研究所，华南应用微生物国家重点实验室，联合培养；
2015/10-2017/11 广东省微生物研究所，华南应用微生物国家重点实验室，博士后；
2018/03-2021/08 中国地质大学（武汉），生物地质与环境地质国家重点实验室，博士后/助理研究员；
2018/04-2019/11 美国迈阿密大学（牛津），地质与环境地球科学系，交流访问；
2021/09-至今 武汉工程大学，环境生态与生物工程学院，特聘教授。
奖励与荣誉
2025 年 武汉工程大学研究生教学成果奖 三等奖 （3/6）；
2025 年 武汉工程大学百佳导师；
2024 年 武汉工程大学优秀班主任；
2017 年 广州市科学技术进步奖（14/15）；
2016 年 广东省微生物研究所 优秀研究生奖励；
2016 年 中国微生物学会学术年会 优秀学术 poster 奖励；
2016 年 全国环境微生物学年会 简浩然优秀论文奖励；
2014 年 广东省遗传学会第九届代表大会暨学术研讨会 优秀学术论文奖励；
2009 年 中南大学 学士学位论文获校优秀论文奖励；
2008 年 中南大学 校级蒋维英大学生奖学金；
代表性科研项目
2026-2029 国家自然科学基金面上项目, 尾矿病毒群落的时空演替及其介导酸化的机制, 42577235, 在研, 主持
2021-2024 国家自然科学基金面上项目, 矿山酸性废水底泥中参与铁硫循环的古菌群落组成与功能的季节性演变, 42077281, 结题, 主持
2017-2019 国家自然科学基金青年科学基金项目, 基于功能活性可视化追踪的芳烃降解微生物高通量筛选方法, 31600077, 结题, 主持
2017中国博士后科学基金面上项目, 芳烃污染物降解中丝状希瓦氏菌形成及调控机理，2017M612622, 结题, 主持
2022-2025 国家重点研发计划绿色生物制造重点专项, 冶金生物关键技术开发及应用, 课题五—离子型稀土矿原位生物浸提新技术, 2022YFC2105305, 在研, 参与
2019-2022 国家自然科学基金重大研究计划, 金属还原地杆细菌到巴氏甲烷八叠球古菌种间电子直接传导的分子机理, 91851211, 结题, 参与
2020-2023 国家自然科学基金重大研究计划, 滇藏热泉微生物介导的碳氮循环及其环境适应机制, 91951205, 结题, 参与
2022-2025 国家自然科学基金委面上项目,热泉微生物介导的硫化物矿物膜的形成机制及其地质学意义, 42172339, 结题, 参与
2020-2023 国家自然科学基金面上项目, 青藏高原湖泊微生物激发效应对沉积物有机碳矿化的影响及其对盐度的响应, 41972317, 结题, 参与
2019-2022 国家自然科学基金面上项目, 热泉嗜热硫酸盐还原菌对有机碳矿化的过程和机理研究—以西藏热泉为例, 41877322, 结题, 参与
2018-2021 国家自然科学基金面上项目, 典型污染区域河流底泥中氯代有机磷阻燃剂的厌氧微生物降解, 41773132, 结题, 参与
2016-2017广东省省级科技计划项目, 广东省环境保护微生物与生态安全创新科研团队建设，2016B070701017, 结题, 参与
代表性学术论文
1. Xikai Su, Jun Liu*, Licao Chang, Wenzhe Hu, Yun Fang*, Jintian Li, Linan Huang, Wensheng Shu, Hailiang Dong. Viral insights into the acidification of sulfidic mine tailings. Journal of Hazardous Materials, 2025, 494:138754.
2. Jianxiong Zeng, Wenzhe Hu, Licao Chang, Zhengshuang Hua, Geng Wu, Yun Fang*, Guowei Wang, Chunqiao Xiao, Jun Liu*. Genome-resolved insights into the bacterial phylum WOR-3: hydrogenotrophic metabolism and unique carbon fixation via archaeal form III RuBisCO. mSystems. 2025, 10:e01178-25.
3. Wenzhe Hu, Yun Fang (co-first author), Brian P. Hedlund, Hongchen Jiang, Yonggang Yang, Chunqiao Xiao, Meiying Xu, Hailiang Dong, Jun Liu*. Insights on adaptive strategies and evolution of cable bacteria in saline lakes. Limnology and Oceanography. 2025.
4. Sha Tan, Jun Liu, Yun Fang (co-first author), Brian Hedlund, Zhenghan Lian, Liying Huang, Jin-tian Li, Linan Huang, Wen-Jun Li, Hongchen Jiang, Hailiang Dong*, Wen-sheng Shu*. Insights into ecological role of a new deltaproteobacterial order Candidatus Acidulodesulfobacterales by metagenomics and metatranscriptomics. The ISME Journal. 2019, 13, 2044-2057.
5. Yun Fang, Jun Liu, Jian Yang, Geng Wu, Zhengshuang Hua, Hailiang Dong, Brian P Hedlund, Brett Baker, Hongchen Jiang*. Compositional and Metabolic Responses of Autotrophic Microbial Community to Salinity in Lacustrine Environments. mSystems. 2022, 7(4):e0033522.
6. Yun Fang, Yang Yuan, Jun Liu, Geng Wu*, Jian Yang, Zhengshuang Hua, Jibin Han, Xiying Zhang, Wenjun Li, Hongchen Jiang*. Casting Light on the Adaptation Mechanisms and Evolutionary History of the Widespread Sumerlaeota. mBio. 2021, 12(2): e00350-21.
7. Yun Fang, Xingjuan Chen, Yin Zhong, Yonggang Yang, Fei Liu, Jun Guo, Meiying Xu*. Molecular mechanism of zero valent iron-enhanced microbial azo reduction. Environmental Pollution. 2021, 290: 0-118046.
8. Yun Fang, Jun Liu, Guannan Kong, Xueduan Liu, Yonggang Yang, Enze Li, Xingjuan Chen, Da Song, Xuejiao You, Guoping Sun, Jun Guo, Meiying Xu*. Adaptive Responses of Shewanella decolorationis to Toxic Organic Extracellular Electron Acceptor Azo Dyes in Anaerobic Respiration. Applied and Environmental Microbiology. 2019, 85(16): e00550-19.
9. Li, Min, Jun Liu, Dan Cao, Xueyi Chen, Jiaxin Shi, Wenzhe Hu, Chunqiao Xiao, Yun Fang*. Heavy metal pollution simplifies microbial networks and enhances modularity during tailings primary succession: divergent assembly dynamics for bacterial and fungal communities. Frontiers in Microbiology. 2025, 16: 1566627.
10. Yun Fang, Chunjie Zhu, Xingjuan Chen, Guoping Sun, Meiying Xu*, Guoping Sun, Jun Guo, Yan Wang, Jinnon Yoo, Cuijuan Tie, Xin Jiang, Xianqiang Li*. Copy number of ArsR reporter plasmid determines its arsenite response and metal specificity. Applied Microbiology and Biotechnology. 2018, 102(13): 5753-5761.
11. Yun Fang, Meiying Xu*, Wei-Min Wu, Chen Xingjuan, Sun Guoping, Guo Jun, Liu Xueduan*. Characterization of the enhancement of zero valent iron on microbial azo reduction. BMC Microbiology. 2015, 15:85-93.
12. Yun Fang, Meiying Xu*, Xingjuan Chen, Guoping Sun, Jun Guo, Wen-Min Wu, Xueduan Liu*. Modified pretreatment method for total microbial DNA extraction from contaminated river sediment. Frontiers of Environmental Science & Engineering. 2015, 9, 444–452.
13. Meiying Xu*, Yun Fang (co-first author), Jun Liu, Xingjuan Chen, Guoping Sun, Zhengshang Hua, Qichao Tu, Wu Liyou, Jizhong Zhou, Xueduan Liu. Draft genome sequence of Shewanella decolorationisstrain S12, a dye-degrading bacterium isolated from a wastewater treatment plant. Genome Announcements. 2013. 1:e00993-00913.
14. Zhijun Zhou, Yun Fang (co-first author), Qihou Li, Yili Liang, Qian Li, Nuo Li, Xinxing Liu, Guanzhou Qiu, Xueduan Liu*. Global transcriptional analysis of stress-response strategies in Acidithiobacillus ferrooxidans ATCC 23270 exposed to organic extractant-Lix984n.World Journal of Microbiology and Biotechnology, 2012, 28(3): 1045-1055.
15. Shi, Jiaxin, Baogang Zhang, Jun Liu*, Yun Fang, Aijie Wang. Spatiotemporal dynamics in microbial communities mediating biogeochemical cycling of nutrients across the Xiaowan Reservoir in Lancang River. Science of the Total Environment. 2022, 813:151862.
16. Jiaoyang Tian, Jingang Hu, Yi Xiong, Xiangyi Deng, Yun Fang, Guowei Wang, Ruan Chi, Chunqiao Xiao*. Metagenomic and metabolomic insights into microalgal-bacterial symbiosis under low carbon-to-nitrogen ratios. Bioresource Technology. 2025, 434: 132849.
17. Lingyan Li, Haitao Wang, Jingang Hu, Yun Fang, Fang Zhou, Junxia Yu, Ruan Chi, and Chunqiao Xiao*. Comparison of microbial communities in unleached and leached ionic rare earth mines. Environmental Science and Pollution Research. 2024, 31(11): 17511-17523.
18. Lingyan Li, Haitao Wang, Jingang Hu, Yaru Duan, Jie Wang, Yun Fang, Jun Wang, Yang Liu, Ruan Chi, Chunqiao Xiao*. Untargeted metabolomics reveals the mechanism for leaching rare earth elements from ion-adsorption rare earth ores using a composite lixiviant. Separation and Purification Technology. 2025, 354: 128917.
19. Haitao Wang, Lingyan Li, Jingang Hu, Yun Fang, Yang Liu, Jun Wang, Ruan Chi, Chunqiao Xiao*. Enhanced leaching process of ion-adsorbed rare earth ores with itaconic acid and magnesium sulfate compound leaching agent. Chemical Engineering and Processing-Process Intensification. 2025, 208: 110137.
20. Yaru Duan, Lingyan Li, Jiale You, Haitao Wang, Yun Fang, Jun Wang, Yang Liu, Ruan Chi, Chunqiao Xiao*. Composite lixiviant synergy for ionic rare earth extraction: Dual-perspective mechanistic insights from metabolomics and mineralogical characterization. Minerals Engineering. 2025, 234: 109766.
21. Yaru Duan, Xingyu Tong, Yixiang Wang, Yun Fang, Jun Wang, Yang Liu, Zhenyue Zhang, Ruan Chi, Chunqiao Xiao*. Selective adsorption of yttrium (III) and ytterbium (III) from rare earth leachate using a phytic acid (C₆H₁₈O₂₄P₆)-modified adsorbent. Hydrometallurgy, 2025, 106574.
22. Yuxin Zhang, Aoqi Li, Ziwei Wang, Yun Fang, Guowei Wang, Junxia Yu, Ruan Chi, Chunqiao Xiao*. Synergistic mechanisms of plant-endophyte detoxification of Cr (VI) in phosphate mining wastelands based on 16S rDNA analysis and metabolomics. Journal of Environmental Chemical Engineering. 2025, 118541.
23. Qiang Fu, Dunfan Yao, Shuqing He, Yun Fang, Guowei Wang*, Jianhua Li, Chunqiao Xiao. Determination of Carbazole Derivatives Associated With Photoelectric Materials in Sediments Using QuEChERS Pretreatment Coupled With Ultra‐High Performance Liquid Chromatography‐High Resolution Mass Spectrometry. Journal of Separation Science 2025, 48(7): e70214.
24. Yushan Chen, Ziwei Wang, Yun Fang, Guowei Wang, Fang Zhou, Junxia Yu, Ruan Chi, Chunqiao Xiao*. Occurrence and microbial remediation of polycyclic aromatic hydrocarbons and heavy metals pollution in soils. World Journal of Microbiology and Biotechnology 2025, 41(8): 280.
25. Jingang Hu, Kai Wan, Xiangyi Deng, Xuemei Liu, Yun Fang, Fang Zhou, Junxia Yu, Ruan Chi, Chunqiao Xiao*. Metagenomic analysis revealed the evolution of microbial communities, metabolic pathways, and functional genes in the heterotrophic nitrification-aerobic denitrification process under La3+ stress. Science of The Total Environment. 2024, 912: 169243.
26. Xifen Zhu, Shaofu Deng, Yun Fang, Sen Yang, Yin Zhong*, Dan Li, Heli Wang, Junhong Wu, Ping’an Peng*. Dehalococcoides-Containing Enrichment Cultures Transform Two Chlorinated Organophosphate Esters. Environmental Science & Technology. 2022, 56, 1951−1962.
27. Yeshen Luo, Fei Liu, Enze Li, Yun Fang, Gang Zhao, Xin Dai, Jianjun Li, Bin Wang, Meiying Xu*, Bing Liao, Guoping Sun. FRET-based fluorescent nanoprobe platform for sorting of active microorganisms by functional properties. Biosensors and Bioelectronics. 2020, 148: 111832.
28. Xianqiang Li*, Xin Jiang, Meiying Xu*, Yun Fang, Yan Wang, Guoping Sun, Jun Guo. Identification of stress-responsive transcription factors with protein-bound Escherichia coli genomic DNA libraries. AMB Express. 2020, 10: 1-14.
29. Yingli Lian, Yonggang Yang, Jun Guo, Yan Wang, Xiaojing Li, Yun Fang, Lixia Gan, Meiying Xu*. Electron acceptor redox potential globally regulates transcriptomic profiling in Shewanella decolorationis S12. Scientific Reports. 2016, 6(1): 1-9.
30. Qihou Li, Nuo Li, Xueduan Liu, Zhijun Zhou, Qian Li, Yun Fang, Xiangru Fan, Xian Fu, Yi Liu, and Huaqun Yin*. Characterization of the acid stress response of Acidithiobacillus ferrooxidans ATCC 23270 based on the method of microarray. Journal of Biological Research. 2012. 17: 3-15.
代表性授权发明专利
刘俊,胡文哲,常利草,方云. 一种 Cr(VI)还原酶及其制备方法和在铬污染水体修复中的应用, 2025-01-07, 中国, 发明专利, ZL202211223747.4
李先强,姜昕,方云,许玫英.一种筛选鉴定胁迫应答基因表达调控因子的方法, 2020-7-20, 中国, 发明专利, ZL202010699515.0
李先强,方云,姜昕,许玫英,郭俊.一类亚砷酸盐抑制因子报告基因质粒及其构建方法和应用, 2019-09-10, 中国, 发明专利, ZL201780001826.1
许玫英,周庆,方云,陈杏娟,孙国萍.一种利用零价铁强化偶氮染料生物降解的方法, 2015-6-24, 中国, 发明专利, ZL201310345316.X
许玫英,方云,陈杏娟,孙国萍.一种复合污染河流底泥微生物总DNA提取的前处理方法, 2015-4-22, 中国, 发明专利, ZL201310089141.0
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